D-Mannose

Urinary tract infections (UTIs), which are infections anywhere along the urinary tract including the bladder and kidneys, are the second most common type of infection in the United States. (1) These infections can be caused by poor hygiene, impaired immune function, the overuse of antibiotics, the use of spermicides, and sexual intercourse. The most common cause, accounting for about 90 percent of all cases, is the transfer of E. coli bacteria from the intestinal tract to the urinary tract.

How should you take D-Mannose for a UTI?

D-Mannose is by far the most effective supplement for both treatment and prevention of UTIs. Similar to glucose in structure, D-mannose is a naturally occurring sugar that is found in a number of fruits, including apples, blueberries, and cranberries. (3) This sugar is the reason that cranberry juice has been commonly recommended as a UTI treatment, though it is far easier to get the recommended dosage from a supplement. D-mannose is effective because it attaches to E. coli bacteria, causing them to stick to each other and preventing them from sticking to the walls of the urinary tract. (4) The bacteria can then easily be eliminated from the body during urination.

D-mannose, even in large quantities, does not cause any adverse side effects, and cannot be metabolized the way other sugars can, meaning this supplement is safe for diabetics and others who are avoiding sugar for any reason. This treatment is also safe for children and the elderly. Symptom relief can be seen as quickly as the following day, and most symptoms are generally resolved after 48 hours of treatment.

Additionally, taking D-mannose during a time where you feel you are most prone to UTIs, such as prior to intercourse or during prolonged antibiotic treatment, can help prevent a UTI from ever developing in the first place. This is especially helpful for those who are prone to chronic UTIs and want to be able to engage in normal life activities without fear of infection.

h2> How does D-Mannose for a UTI work?

The typical dose of D-mannose for UTI treatment is 500 mg, in capsule or powder form, taken in a glass of water or juice every two to three hours for five days. (5) It is a good practice to continue taking the supplement even after symptoms have diminished to ensure complete elimination of the bacteria in the urinary tract. This dose can also be taken as a preventative, or prophylactic, method.

While there have not been any peer reviewed research to support the effectiveness of D-mannose in treating or preventing UTIs, clinical and anecdotal experience suggests it is highly effective for the majority of infections, both acute and chronic. Some of my patients who have used D-mannose as a UTI treatment method have even described its effects as miraculous.

D-mannose, when used properly, is relatively safe for those already in good health, with the most common side effects being diarrhea and bloating, though some resources warn that it could harm the kidneys in large doses. D-mannose is generally not recommended for those with diabetes or for women who are pregnant or breastfeeding (definitely check with your doctor if you fall into one of those categories). There also aren’t many studies on the use of D-mannose, so effective/safe dosing hasn’t been studied extensively.